behaves like Bn ether.very bulky, so better selectivity towards primary alcohol.
forming:
trityl chloride, TEA, DCM
easily falled off when contact with Silica gel.(during column)
pretreat the silica gel with 1% TEA in P.E. can prevent it completely.
can be removed by hydrogenation(pd/c, H2), addition of Py can preserve it.
Thursday, November 15, 2007
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