Saturday, October 6, 2007


less basic than organolithium?

usually stable in THF at rt. Can be made in reflux THF or ether.

1,2 addition. (for enolizable/stericly hindered ketones, use CeCl3)

To initiate the reaction between halides and Mg,
1. heat,
2. I2 can be used.
3. broken glass can also be used.
4. distill organohalides with CaH2 can also help.

Reaction is very exothermic.
usually, Grignard made from RBr is more reacitive than RCl.

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