Wednesday, August 15, 2007

asymmetric epoxidation

Sharpless epoxidation
allylic alcohol only.
homoallylic alcohol can also be reactive using some more active metal.

Jacobsen epoxidation

not limited to allylic alcohol, tetra-sub alkene gives low ee.

Shi epoxidation

Sulfur Ylide Epoxidation

cordova's epoxidation
works for electron deficient olefins.

taber's mandelic acid approachbased on column separation of two mandelic ester diasteromers.
Works on Terminal alkenes.

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