Showing posts with label synthesis. Show all posts
Showing posts with label synthesis. Show all posts

Tuesday, July 7, 2009

Overmann synthesis of Actinophyllic Acid

Overman, Martin and Rohde. JACS, 2008, ASAP. DOI: 10.1021/ja803158y.

although it is racemic, it still went to jacs.
key step:

















aza-Cope Mannich.

some molecular accomplished by this method: