Nature did this transformation using an enzyme to oxidize the 25 postion directly.
there is no chemical ways with acceptable yield for this transformation yet.
Thursday, November 15, 2012
Transformation wanted!
This reaction will be very useful if can be done！
25-hydroxy Vitamin D2 is an important intermediate for many VD2 analogs such as paricalcitol.
Nature did this transformation using an enzyme to oxidize the 25 postion directly.
there is no chemical ways with acceptable yield for this transformation yet.
Nature did this transformation using an enzyme to oxidize the 25 postion directly.
there is no chemical ways with acceptable yield for this transformation yet.
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