The 1,2-dimagnesiummethylbenzene showing below is a useful reagent for metal ligand preparation.
This di-grignard reagent can be made in high yield from corresponding dichloride compound.
1,2-Dibromomethylbenzene can't be used because it can cause problem.
steps:
1. activate Mg using 1,2-dibromoethane.
2. in diluted solution, slowly add dichloride into Mg in THF. control temperature at rt.
3. allow 8 hr stirring at rt.
yield is over 95% in reports.
Thursday, July 14, 2011
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1 comment:
good one
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