Thursday, February 5, 2009

why methyl alpha-D-glucopyranoside is more stable than beta?

methyl alpha-D-glucopyranoside is so cheap, 1 kg =$50 ,
methyl beta-d-glucopyranoside is so expensive, 5 g=$50

alpha-D-glu has an axial methoxy, but more stable,
beta-D-glu has the methoxy equatorial, but less stable,

why?
answers are in this link:

http://www.cem.msu.edu/~reusch/VirtualText/carbhyd.htm

looking for: anomeric effect.

1 comment:

Unknown said...

Physcion 8-β-D-glucoside has been studied in research relating to the treatment of the glomerulonephritis. It is the glucoside of Physcion (P398000) which is a natural anthraquinone derivative, on the infection process of Blumeria graminis on wheat. Physcion-8-O-β-D-glucopyranoside