Organosynthetic & Organometallic Chemistry
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Friday, April 11, 2008
t-butyldimethylsilane ether
Formation:
tbdmsCl/TEA/DMF, 4-dmap, rt.
primary alcohol protected selectively.
under acid condition (trace h2so4 in mecn, 50C) the silane ether can fall off.
deprotection:
TBAF.
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