Organosynthetic & Organometallic Chemistry
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Monday, September 10, 2007
alkylidene carbene insertion
formation: vinyl halide (-70C, DME, KHMDS).
or ketone + (Li-TMSdiazomethane), aldehyde will give (alkyne?)
the above reactions are very sensitive to steric hinderance. In my experience, ketone with a alpha quartary center can't react.
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